Meg Ryan: 'Work Ruins Romance' 8/20/08

Actress Meg Ryan will never have a long term relationship with a man - because she deems love impossible in Hollywood.

The Sleepless in Seattle star was married to actor Dennis Quaid, but their marriage ended when she had an affair with Russell Crowe in 2000.

And Ryan has ruled out a long term relationship, because she believes there is a Hollywood curse.

She tells Britain's Hello magazine, "It's very difficult to be a career person and have a relationship. I didn't succeed at doing it at all. it's incredibly hard."